Comparative Genomics

In the absence of a conifer genome sequence, and in light of this putative synteny, comparative genomics becomes an important tool for integrating information across the Pinaceae.  Among conifers, the largest effort in genetics and genomics has been devoted to loblolly pine, with large EST collections, rich genetic resources, and well developed genetic and QTL maps.  Species of spruce rank second, largely because of Genome Canada funded projects.  Loblolly pine and spruce bridge the pine family.  Besides reinforcing each other, joint genomic patterns in these two species might enable extension and integration of such genomic knowledge into other species; particularly lodge pole pine and Douglas-fir.

 

Differences among genotypes, populations, and transfer of genomic information between spruce and pine will further advance knowledge about defense mechanisms.  We are pursuing these differences by means of: 

  1. identification of candidate genes for resistance, verification and re-sequencing;
  2. QTL and association studies of resistance;
  3. mapping of gene expression profiles in families segregating for weevil resistance;
  4. detection of unusual evolutionary patterns among species (spruce-pine, spruce-Arabidopsis) in candidate genes;
  5. characterization of synteny between loblolly pine both a the genetic map level and at the sequence level (using BACs).
 

Funding Institutions

UBC Genome Canada
Genome British Columbia